This course explores a biosemiotic approach to art, our body and mind. It engages with the intrigue of meaning seeking and interpreting that has been regarded as an essential point of contact between various disciplines such as anthropology, philosophy, art history, psychology and zoology. While coping with ambiguities and uncertainties in nature and culture, we may wonder about the approach or the path we should be taking so as to survive. Thus, this course draws on the parallel between our survival in everyday situations and that in the academia. Key issues to engage with include: (1) how we can make the most use of our instinct, intuition or presumption in dealing with incomplete forms or seemingly unorganized data and information; (2) how we may adjust our attitude so as to foster the ethics and approaches of working together with other minds or entities. All in all, this course encourages students to equip themselves with perspectives and skills of various disciplines with a view to better surviving the world of opinions in the arts and humanities.